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Research & education only — not financial advice.TENK is not a registered investment adviser; calls are impersonal, generated from SEC filings and a delayed/third-party price feed, and may be wrong or out of date. The operator and an affiliated trading operation may hold or trade the securities TENK rates — see Disclosures. Do your own research.

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Home›Stocks›NAUT
NAUT logo

NAUT

Nautilus Biotechnology, Inc.

Next earnings Jul 29, 2026 · consensus $-0.14 EPS

Last earnings +0.8% on 2026-04-28

Avoid
$1.73
▼ -3.35%
$1.73▲ +149.28%
over 1Y
L $0.64H $3.95
Earnings Dividend Split Congress buy Congress sellGrouped by date · hover a pin to expand
Today-3.4%
1W-23.8%
1M-35.4%
3M-47.7%
YTD-9.4%
1Y+149.3%
OverviewFinancialsValuationQualityTimelineFilings
Rating
Avoid
Quality
C-
Valuation
Fair value
Filings
Flagged
Avoid
Conviction
Horizon
Long (>12mo)
Street · 8 analysts
Buy

Pre-revenue proteomics developer burning ~$51M/yr with $12.4M cash and no commercial product — a binary bet, not an investable business.

Net income -$59.0M · FY2025

Nautilus is a self-described "development stage life sciences company" that, by its own 10-K, has "not generated any revenue from our Nautilus platform or other sources since inception" and "do not have any products available for commercial sale." The revenue line is blank in every year FY2021–FY2025, while net losses have compounded (-$50.3M → -$70.8M, then -$59.0M in FY2025). The FY2025 improvement to -$59.0M is not traction — it is belt-tightening: R&D fell 18.6% to $41.1M and capex was cut ~40% to $1.28M, the signature of a company conserving cash rather than accelerating toward launch.

The balance sheet is the crux. Cash & equivalents collapsed 55.2% to just $12.4M, and total assets fell 21.3% to $191M as the company funded a -$50.7M operating cash burn. Even counting the broader $106M of current assets (cash plus marketable securities) against a ~$51M annual burn, that is roughly two years of runway before the balance sheet forces action. Management is explicit: "We expect that we will need to raise additional capital to fund our development and commercialization plans, which may not be available to us on favorable terms or at all." With 127M shares already out and the stock at $1.73, any raise on unfavorable terms means heavy dilution from a depressed price — the worst kind. The low 0.22x liabilities/equity ratio is cosmetically reassuring but irrelevant when the equity itself ($157M, down 24.8%) is being consumed and accumulated deficit sits at -$332M.

Is NAUT a buy? The one-page verdict, explained →

The options angle

model · matches our verdict
Bear put spread (caution)~90d expiry
  • Long put 1.5 @ ~0.14 est
  • Short put 1.5 @ ~0.14 est
debit $0max +$0max $0

AVOID means we wouldn't engage at all — if expressing the short side anyway, only with capped risk.

Open in the calculator →

Educational template, not a trade recommendation. Strikes and premiums are Black-Scholes model estimates from the last close and 30-day realized volatility — real chains, spreads and IV will differ. Options involve substantial risk.

Financials · annual, by fiscal year

Line itemFY21FY22FY23FY24FY25
Revenue—————
Gross profit—————
Operating income—————
Net income-$50.3M-$57.9M-$63.7M-$70.8M-$59.0M
Diluted EPS-$0.60-$0.46-$0.51-$0.56-$0.47
Net margin—————

10-year statements — income, cash flow, balance sheet & CSV export →

Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.

Key statistics

Valuation

Enterprise value$207M
EV / EBITDA—
EV / Sales—
EV / FCF—
P / FCF—
PEG (trailing)—
Earnings yield-26.8%
FCF yield-23.6%

Quality & risk

ROIC (est.)—
Free cash flow-$52.0M
Total debt—
Net cash$12.4M
Piotroski F-Score1/6

Capital returns

Buyback yield—
Dividend yield (est.)—
Shareholder yield—
Shares Δ YoY+0.3%

Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.

Disclosure timeline

SEC · 8-Ks + reports
Recent disclosure tone has skewed negative — read the flagged items.
  1. 8-K Shareholder vote2026-06-18

    Annual meeting voting results reported; routine governance, no financial impact

  2. 8-K Earnings results2026-04-28

    Q1 2026: still no revenue; cash equivalents thin against ~$50M annual burn

  3. DEF 14A Proxy statement2026-04-28

    Q1 2026: still no revenue; cash equivalents thin against ~$50M annual burn

  4. 10-Q Quarterly report2026-04-28

    Q1 2026: still no revenue; cash equivalents thin against ~$50M annual burn

  5. 8-K Earnings results2026-02-26

    FY2025: loss narrowed to $59M but cash -55% to $12.4M; funding runway a risk

  6. 10-K Annual report2026-02-26

    FY2025: loss narrowed to $59M but cash -55% to $12.4M; funding runway a risk

  7. 8-K Other event2025-11-04

    Other-events disclosure (Item 8.01); material update outside routine earnings

  8. 8-K Earnings results2025-10-28

    Q3 2025: development-stage losses persist, Voyager still pre-launch

  9. 10-Q Quarterly report2025-10-28

    Q3 2025: development-stage losses persist, Voyager still pre-launch

Recent filings

all on EDGAR ↗
SCHEDULE 13D/AFiling2026-06-30open ↗4Period ending 2026-06-182026-06-22open ↗4Period ending 2026-06-182026-06-22open ↗4Period ending 2026-06-182026-06-22open ↗4Period ending 2026-06-182026-06-22open ↗4Period ending 2026-06-182026-06-22open ↗8-KPeriod ending 2026-06-172026-06-18open ↗SCHEDULE 13D/AFiling2026-06-04open ↗4Period ending 2026-06-022026-06-04open ↗ARSPeriod ending 2025-12-312026-04-28open ↗DEFA14AFiling2026-04-28open ↗DEF 14APeriod ending 2026-06-172026-04-28open ↗

Quality score

C-
ValueGrowthProfitHealthMom.
Value—
GrowthA-
ProfitabilityF
Financial healthB-
MomentumF
  • ✗Profitable (positive net income)
  • ✗Return on equity above 15%
  • ✓Liabilities below 2× equity
0.6452-week3.95
Revenue
—
Net margin
—
ROE
-37.6%
P/E
—

SEC fundamentals · FY 2025

■ revenue · ■ net income, by fiscal year

Net income-$59.0M+16.6%
Diluted EPS-$0.47+16.1%
Cash & equivalents$12.4M-55.2%
Total assets$191M-21.3%
Total liabilities$34.1M+0.4%
Stockholders' equity$157M-24.8%
L/E: 0.22x

Frequently asked

Is Nautilus Biotechnology, Inc. (NAUT) a buy?
NAUT currently carries a Avoid rating with 4/5 conviction, derived from its latest SEC filings. Pre-revenue proteomics developer burning ~$51M/yr with $12.4M cash and no commercial product — a binary bet, not an investable business.
What is Nautilus Biotechnology, Inc.'s quality score?
NAUT scores 52.34213029673111/100 (grade C-) on a SEC-grounded quality model spanning value, growth, profitability, financial health and momentum.

Sources: SEC EDGAR (CIK 0001808805, latest 10-Q filed 2026-04-28) · EODHD · Proprietary analysis · as of 7/3/2026, 11:02:34 AM.

›About this recommendation — produced by TENK/calls (tenkcalls.com), Luxembourg · not investment advice

AI-generated analysis, produced by our proprietary engine from SEC filing data.

Investment recommendation produced by TENK/calls (tenkcalls.com), Luxembourg. Completed Jul 3, 2026, 7:02 AM ET. Ratings & methodology: definitions · All recommendations to date: track record · Conflicts: disclosures. Not investment advice.

Research and education only — not financial advice. TENKis not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities TENK rates; see Disclosures. Past performance does not guarantee future results. Do your own research.

Insider activity

Form 4 · SEC

Last 90 days: 0 open-market buys · 2 sales

2026-06-02
AH Equity Partners Bio II, L.L.C.
10% owner
Sell4.62M @ $2.35$10.8M
2026-06-02
AH Equity Partners Bio II, L.L.C.
10% owner
Sell384K @ $2.35$902K
2026-03-04
Patel Sujal M
CEO, President, and Secretary
Buy25.0K @ $2.61$65.2K

Earnings history

beat/miss · move
2026-04-28Beat +18.9% est▲ +12.45%8-K ↗
2026-02-26Beat +23.0% est▼ -14.18%8-K ↗
2025-10-28Beat +28.1% est▲ +9.02%8-K ↗
2025-07-31Beat +24.1% est▼ -0.13%8-K ↗
2025-04-29—▲ +0.76%8-K ↗
2025-02-27—▼ -15.58%8-K ↗

Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.

Vs tracked universe

compare →

1195 tracked peers · median

TENK Score52 vs 67
Revenue growth— vs 7.5%
Net margin— vs 10.0%
Return on equity-37.6% vs 12.0%
P/E— vs 26.2