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Research & education only — not financial advice.TENK is not a registered investment adviser; calls are impersonal, generated from SEC filings and a delayed/third-party price feed, and may be wrong or out of date. The operator and an affiliated trading operation may hold or trade the securities TENK rates — see Disclosures. Do your own research.

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TTENK/calls
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TTENK/calls
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Home›SEPN›Financials
Annual statements · SEC XBRL · FY2023 – FY2025

Septerna, Inc. (SEPN) financials

Income statement

Septerna, Inc. (SEPN) income statement, annual, from SEC filings
Fiscal yearFY2023FY2024FY2025
Revenue$151K$1.07M$46.0M
Revenue growth—611.9%4174.5%
Operating income$2.08M-$80.8M-$68.3M
Operating margin1374.2%-7518.4%-148.6%
Net income$4.18M-$71.8M-$48.9M
Net margin2768.2%-6678.9%-106.4%
EPS (diluted)$0.29-$7.26-$1.10

Cash flow

Septerna, Inc. (SEPN) cash flow, annual, from SEC filings
Fiscal yearFY2023FY2024FY2025
Operating cash flow-$38.7M-$67.5M$110M
Capital expenditures$2.88M$2.10M$518K
Free cash flow-$41.6M-$69.6M$110M

Balance sheet

Septerna, Inc. (SEPN) balance sheet, annual, from SEC filings
Fiscal yearFY2023FY2024FY2025
Cash & equivalents$88.5M$238M$121M
Total assets$131M$457M$596M
Total liabilities$20.0M$36.5M$214M
Shareholders' equity-$38.4M$420M$382M
Retained earnings-$46.6M-$118M-$167M
Shares (wtd avg diluted)2.18M9.89M44.3M

Every figure is extracted from Septerna, Inc.’s annual reports as filed with the SEC (XBRL company facts) — no third-party estimates. Fiscal years are labeled by period end; filers occasionally re-tag concepts, so a sparse cell means the company didn’t report that concept for that year. Free cash flow = operating cash flow − capital expenditures.

Common questions

What is Septerna, Inc.'s annual revenue?
Septerna, Inc. (SEPN) reported $46.0M of revenue for fiscal year 2025 — up 4174.5% from $1.07M in FY2024, per its annual report filed with the SEC.
Is Septerna, Inc. profitable?
Not in FY2025 — SEPN reported a net loss of $48.9M, per SEC filings.
What is Septerna, Inc.'s free cash flow?
$110M in FY2025 (operating cash flow $110M minus $518K of capital expenditures), from the SEC cash-flow statement.
Does SEPN pay a dividend?
Septerna, Inc. reported no cash dividends paid in FY2025, per its SEC cash-flow statement.
Full SEPN analysis — verdict, score & filings →Is SEPN a buy? →

Research and education only — not financial advice. TENKis not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities TENK rates; see Disclosures. Past performance does not guarantee future results. Do your own research.