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Research & education only — not financial advice.TENK is not a registered investment adviser; calls are impersonal, generated from SEC filings and a delayed/third-party price feed, and may be wrong or out of date. The operator and an affiliated trading operation may hold or trade the securities TENK rates — see Disclosures. Do your own research.

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Home›SPRO›Financials
Annual statements · SEC XBRL · FY2016 – FY2025

Spero Therapeutics, Inc. (SPRO) financials

Income statement

Spero Therapeutics, Inc. (SPRO) income statement, annual, from SEC filings
Fiscal yearFY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue$335K$1.98M$3.97M$4.74M$258K$3.07M$2.50M$933K$371K$12.6M
Revenue growth—490.7%100.4%19.6%-94.6%1089.9%-18.5%-62.7%-60.2%3292.5%
Operating income-$33.2M-$41.7M-$42.8M-$63.2M-$79.1M-$88.0M-$42.2M$21.5M-$73.4M$6.31M
Operating margin-9916.7%-2108.6%-1079.3%-1333.1%-30664.0%-2865.5%-1685.9%2302.4%-19773.9%50.2%
Net income-$25.5M-$38.7M-$41.7M-$60.9M-$78.3M-$89.8M-$46.4M$22.8M-$68.6M$8.57M
Net margin-7609.3%-1957.7%-1051.4%-1284.3%-30348.8%-2925.1%-1854.4%2444.4%-18481.4%68.1%
EPS (diluted)-$95.87-$17.82-$2.60-$3.35-$3.52-$2.91-$1.23$0.43-$1.27$0.15

Cash flow

Spero Therapeutics, Inc. (SPRO) cash flow, annual, from SEC filings
Fiscal yearFY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Operating cash flow-$29.0M-$39.1M-$39.6M-$50.0M-$85.9M-$64.3M-$7.73M-$33.0M-$23.4M-$12.6M
Capital expenditures$830K$27.0K$2.44M$314K$157K—————
Free cash flow-$29.8M-$39.1M-$42.1M-$50.3M-$86.0M—————

Balance sheet

Spero Therapeutics, Inc. (SPRO) balance sheet, annual, from SEC filings
Fiscal yearFY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash & equivalents$10.3M$87.3M$34.1M$29.7M$85.2M$113M$109M$76.3M$52.9M$40.3M
Total assets$13.8M$93.5M$129M$106M$153M$171M$125M$182M$111M$68.9M
Total liabilities$7.41M$8.52M$13.2M$31.5M$21.4M$82.8M$48.9M$75.5M$64.4M$9.90M
Shareholders' equity-$45.4M$84.6M$116M$74.6M$132M$88.3M$75.9M$107M$46.1M$59.0M
Retained earnings-$45.4M-$96.8M-$139M-$199M-$278M-$367M-$414M-$391M-$460M-$451M
Shares (wtd avg diluted)—14.4M17.2M19.2M29.3M30.9M37.6M53.0M54.0M59.0M

Every figure is extracted from Spero Therapeutics, Inc.’s annual reports as filed with the SEC (XBRL company facts) — no third-party estimates. Fiscal years are labeled by period end; filers occasionally re-tag concepts, so a sparse cell means the company didn’t report that concept for that year. Free cash flow = operating cash flow − capital expenditures.

Common questions

What is Spero Therapeutics, Inc.'s annual revenue?
Spero Therapeutics, Inc. (SPRO) reported $12.6M of revenue for fiscal year 2025 — up 3292.5% from $371K in FY2024, per its annual report filed with the SEC.
Is Spero Therapeutics, Inc. profitable?
Yes — SPRO earned $8.57M of net income in FY2025, a 68.1% net margin, per SEC filings.
Does SPRO pay a dividend?
Spero Therapeutics, Inc. reported no cash dividends paid in FY2025, per its SEC cash-flow statement.
Full SPRO analysis — verdict, score & filings →Is SPRO a buy? →

Research and education only — not financial advice. TENKis not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities TENK rates; see Disclosures. Past performance does not guarantee future results. Do your own research.