As of the latest Form 4 filed Mar 20, 2026.
What Opko Health Inc insiders — officers, directors and 10% owners — have bought and sold in their own stock, straight from their SEC Form 4 filings. Values are shares × the reported transaction price where both are disclosed.
Buys plotted up, sells down; bar height is the disclosed dollar value (shares × reported price). Our Form 4 history is only complete from mid-2026, so early months are sparse — the series fills in as more filings land. Open-market purchases and sales only.
Newest filing first — the 25 most recent filings for OPK.
| Filed | Trade date | Insider | Transaction | Shares | Price | Value | 10b5-1 | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-03-20 | 2026-03-20 | PAGANELLI JOHN A Director | PPurchase | +10.0K | $1.14 | $11.3K | No | Form 4 ↗ |
| 2025-11-21 | 2025-11-21 | FROST PHILLIP MD ET AL CEO & Chairman | PPurchase | +193K | $1.34 | $257K | No | Form 4 ↗ |
| 2025-11-21 | 2025-11-21 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +191K | $1.33 | $255K | No | Form 4 ↗ |
| 2025-11-21 | 2025-11-21 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +89.4K | $1.33 | $118K | No | Form 4 ↗ |
| 2025-11-21 | 2025-11-21 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +3.89K | $1.32 | $5.14K | No | Form 4 ↗ |
| 2025-11-21 | 2025-11-21 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +102K | $1.30 | $133K | No | Form 4 ↗ |
| 2025-11-20 | 2025-11-20 | FROST PHILLIP MD ET AL CEO & Chairman | PPurchase | +13.7K | $1.35 | $18.4K | No | Form 4 ↗ |
| 2025-11-20 | 2025-11-20 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +1.76K | $1.35 | $2.36K | No | Form 4 ↗ |
| 2025-11-20 | 2025-11-20 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +24.6K | $1.34 | $32.9K | No | Form 4 ↗ |
| 2025-11-20 | 2025-11-20 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +162K | $1.34 | $216K | No | Form 4 ↗ |
| 2025-11-20 | 2025-11-20 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +212K | $1.33 | $282K | No | Form 4 ↗ |
| 2025-11-20 | 2025-11-20 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +47.1K | $1.33 | $62.4K | No | Form 4 ↗ |
| 2025-11-20 | 2025-11-20 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +119K | $1.32 | $157K | No | Form 4 ↗ |
| 2025-11-19 | 2025-11-19 | FROST PHILLIP MD ET AL CEO & Chairman | PPurchase | +155K | $1.32 | $205K | No | Form 4 ↗ |
| 2025-11-19 | 2025-11-19 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +199K | $1.32 | $262K | No | Form 4 ↗ |
| 2025-11-19 | 2025-11-19 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +66.5K | $1.31 | $87.1K | No | Form 4 ↗ |
| 2025-11-19 | 2025-11-19 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +13.0K | $1.31 | $17.0K | No | Form 4 ↗ |
| 2025-11-19 | 2025-11-19 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +30.1K | $1.30 | $39.1K | No | Form 4 ↗ |
| 2025-11-19 | 2025-11-19 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +21.2K | $1.30 | $27.5K | No | Form 4 ↗ |
| 2025-11-19 | 2025-11-19 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +300.00 | $1.29 | $387.00 | No | Form 4 ↗ |
| 2025-11-19 | 2025-11-19 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +58.2K | $1.29 | $74.7K | No | Form 4 ↗ |
| 2025-11-19 | 2025-11-19 | FROST PHILLIP MD ET AL, CEO & Chairman | PPurchase | +36.3K | $1.28 | $46.5K | No | Form 4 ↗ |
| 2025-10-31 | 2025-10-31 | FROST PHILLIP MD ET AL CEO & Chairman | PPurchase | +150K | $1.42 | $213K | No | Form 4 ↗ |
| 2025-08-19 | 2025-08-18 | FROST PHILLIP MD ET AL CEO & Chairman | GGift | −440K | $0.00 | $0.00 | No | Form 4 ↗ |
| 2025-08-08 | 2025-08-08 | FROST PHILLIP MD ET AL CEO & Chairman | PPurchase | +675K | $1.32 | $891K | No | Form 4 ↗ |
Insiders — a company’s officers, directors and holders of more than 10% of its stock — must report any trade in that stock to the SEC on a Form 4 within two business days. Each row here is one transaction from those filings.
The transaction code tells you what happened: Purchase (P) and Sale (S) are open-market trades — the ones markets watch most; Award (A) is a granted stock or unit, Option exercise (M) converts options into shares, and Gift (G) is a transfer for no consideration. Awards, exercises and gifts are largely compensation or administrative, not a directional bet.
One caveat on sales: many are made under a Rule 10b5-1 plan scheduled months in advance, so a sale is not automatically a bearish signal. Insider activity is a noisy input — read it alongside the filings, not on its own.
See also OPK’s full analysis or the market-wide insider trading feed. The tabs above jump to OPK’s other SEC data.
Source: SEC Form 4 filings for OPK, parsed from EDGAR. Transaction prices are as reported in the filing — SEC public-domain data, not market quotes. Values are shares × reported price where both are disclosed; grants and gifts often carry no price. A delayed record of what insiders reported, not a live position or a recommendation.
Research and education only — not financial advice. TENKis not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities TENK rates; see Disclosures. Past performance does not guarantee future results. Do your own research.