Equal-weight biotech.
We resolve 87% of XBI’s reported NAV to covered tickers; the remaining ~13% is cash, non-equity, foreign lines and names we don’t cover — the honest tail of a CUSIP-based resolution, not a data gap you should read as holdings we hid.
Covered positions by weight, as of 2026-03-31. Each links to its stock page and our full verdict.
| # | Holding | Our call | % of NAV | Value |
|---|---|---|---|---|
| 1 | MDGL | Buy | 1.38% | $103M |
| 2 | TGTX | Hold | 1.35% | $100M |
| 3 | INSM | Hold | 1.34% | $99.4M |
| 4 | SRRK | Hold | 1.30% | $96.5M |
| 5 | APGE | Hold | 1.28% | $95.5M |
| 6 | PTGX | Hold | 1.24% | $92.5M |
| 7 | SMMT | Avoid | 1.24% | $92.3M |
| 8 | UTHR | Buy | 1.24% | $92.2M |
| 9 | PRAX | Avoid | 1.24% | $91.9M |
| 10 | ARWR | Hold | 1.23% | $91.4M |
| 11 | COGT | Hold | 1.22% | $90.4M |
| 12 | BBIO | Hold | 1.19% | $88.1M |
| 13 | PTCT | Hold | 1.18% | $87.9M |
| 14 | CYTK | Avoid | 1.18% | $87.8M |
| 15 | ALNY | Buy | 1.18% | $87.5M |
| 16 | EXEL | Buy | 1.17% | $87.0M |
| 17 | NUVL | Hold | 1.17% | $86.8M |
| 18 | KYMR | Hold | 1.16% | $86.6M |
| 19 | CGON | Avoid | 1.16% | $86.4M |
| 20 | NTRA | Hold | 1.16% | $86.2M |
| 21 | NBIX | Buy | 1.16% | $86.2M |
| 22 | TWST | Hold | 1.16% | $85.9M |
| 23 | KRYS | Buy | 1.15% | $85.8M |
| 24 | PCVX | Avoid | 1.15% | $85.6M |
| 25 | MIRM | Buy | 1.15% | $85.3M |
| 26 | IONS | Buy | 1.14% | $85.1M |
| 27 | TVTX | Hold | 1.14% | $85.1M |
| 28 | REGN | Hold | 1.14% | $84.5M |
| 29 | INCY | Hold | 1.13% | $84.2M |
| 30 | CELC | Hold | 1.12% | $83.5M |
| 31 | RVMD | Avoid | 1.11% | $82.7M |
| 32 | HALO | Buy | 1.11% | $82.4M |
| 33 | RYTM | Hold | 1.10% | $81.9M |
| 34 | BIIB | Hold | 1.10% | $81.6M |
| 35 | ARQT | — | 1.09% | $81.0M |
| 36 | ABBV | Hold | 1.09% | $80.9M |
| 37 | GILD | Hold | 1.09% | $80.9M |
| 38 | BMRN | Buy | 1.07% | $79.3M |
| 39 | AMGN | Hold | 1.06% | $79.0M |
| 40 | IBRX | Avoid | 1.06% | $78.6M |
| 41 | BEAM | — | 1.04% | $77.4M |
| 42 | VKTX | Hold | 1.04% | $77.1M |
| 43 | MRNA | Avoid | 1.03% | $76.9M |
| 44 | VRTX | Hold | 1.03% | $76.8M |
| 45 | ERAS | Avoid | 1.03% | $76.6M |
| 46 | ACAD | — | 1.02% | $76.0M |
| 47 | SRPT | — | 0.89% | $66.5M |
| 48 | AGIO | — | 0.88% | $65.3M |
| 49 | RARE | — | 0.88% | $65.1M |
| 50 | IRON | — | 0.87% | $64.7M |
| 51 | IMNM | — | 0.86% | $64.2M |
| 52 | IMVT | Avoid | 0.86% | $63.8M |
| 53 | BCRX | — | 0.85% | $63.4M |
| 54 | DYN | — | 0.84% | $62.3M |
| 55 | CPRX | — | 0.76% | $56.2M |
| 56 | SNDX | — | 0.74% | $54.7M |
| 57 | DNLI | — | 0.73% | $54.4M |
| 58 | IDYA | — | 0.73% | $54.3M |
| 59 | SYRE | Hold | 0.73% | $53.9M |
| 60 | GRAL | — | 0.72% | $53.8M |
| 61 | VRDN | — | 0.70% | $52.2M |
| 62 | RXRX | — | 0.69% | $51.4M |
| 63 | KOD | — | 0.69% | $51.2M |
| 64 | DNTH | Hold | 0.66% | $49.2M |
| 65 | NTLA | — | 0.65% | $48.1M |
| 66 | MLYS | — | 0.65% | $48.0M |
| 67 | RCUS | — | 0.63% | $46.7M |
| 68 | ARDX | — | 0.62% | $45.9M |
| 69 | ADMA | — | 0.60% | $44.3M |
| 70 | NRIX | — | 0.59% | $43.6M |
| 71 | TNGX | Avoid | 0.56% | $41.3M |
| 72 | CLDX | — | 0.52% | $38.8M |
| 73 | NVAX | — | 0.51% | $38.0M |
| 74 | ORKA | Avoid | 0.50% | $37.3M |
| 75 | STOK | — | 0.49% | $36.7M |
| 76 | VCEL | — | 0.48% | $35.9M |
| 77 | CAPR | — | 0.48% | $35.6M |
| 78 | PVLA | — | 0.46% | $34.2M |
| 79 | GLUE | — | 0.44% | $32.4M |
| 80 | CRVS | — | 0.42% | $31.0M |
| 81 | IOVA | — | 0.38% | $28.6M |
| 82 | ANAB | — | 0.38% | $28.4M |
| 83 | RLAY | — | 0.38% | $28.2M |
| 84 | MNKD | — | 0.36% | $26.8M |
| 85 | TSHA | — | 0.34% | $25.2M |
| 86 | TYRA | — | 0.34% | $25.1M |
| 87 | GERN | — | 0.33% | $24.8M |
| 88 | PGEN | — | 0.31% | $23.2M |
| 89 | VIR | — | 0.30% | $22.6M |
| 90 | KALV | — | 0.29% | $21.7M |
| 91 | CTMX | — | 0.29% | $21.2M |
| 92 | KURA | — | 0.28% | $20.5M |
| 93 | INBX | — | 0.27% | $19.9M |
| 94 | SLS | — | 0.27% | $19.8M |
| 95 | JANX | — | 0.27% | $19.8M |
| 96 | CMPX | — | 0.26% | $19.5M |
| 97 | SVRA | — | 0.26% | $19.4M |
| 98 | RIGL | — | 0.26% | $19.2M |
| 99 | SANA | — | 0.26% | $19.2M |
| 100 | CGEM | — | 0.25% | $18.6M |
| 101 | SPRY | — | 0.24% | $17.8M |
| 102 | ZBIO | — | 0.24% | $17.7M |
| 103 | XNCR | — | 0.23% | $17.2M |
| 104 | REPL | — | 0.23% | $16.8M |
| 105 | SION | — | 0.22% | $16.7M |
| 106 | VOR | — | 0.22% | $16.6M |
| 107 | AVBP | — | 0.22% | $16.2M |
| 108 | IRWD | — | 0.19% | $14.0M |
| 109 | BCAX | — | 0.19% | $14.0M |
| 110 | PRME | — | 0.19% | $13.9M |
| 111 | ALT | — | 0.18% | $13.4M |
| 112 | ABSI | — | 0.18% | $13.3M |
| 113 | EBS | — | 0.18% | $13.1M |
| 114 | ALLO | — | 0.17% | $12.7M |
| 115 | PURR | — | 0.17% | $12.5M |
| 116 | FDMT | — | 0.17% | $12.3M |
| 117 | VNDA | — | 0.16% | $11.8M |
| 118 | RGNX | — | 0.15% | $11.4M |
| 119 | LXEO | — | 0.14% | $10.7M |
| 120 | VSTM | — | 0.14% | $10.7M |
| 121 | ABUS | — | 0.14% | $10.2M |
| 122 | MYGN | — | 0.13% | $9.72M |
| 123 | OCGN | — | 0.13% | $9.45M |
| 124 | RCKT | — | 0.13% | $9.33M |
| 125 | MDXG | — | 0.12% | $9.02M |
| 126 | AKBA | — | 0.11% | $8.39M |
| 127 | AVXL | — | 0.11% | $8.15M |
| 128 | IVVD | — | 0.10% | $7.35M |
| 129 | CATX | — | 0.10% | $7.15M |
| 130 | DMRA | — | 0.03% | $2.43M |
Source: SEC Form N-PORT-P (the fund’s latest public fiscal-quarter-end report, filed ~2 months after the period). Weights and values are as reported in the filing — a delayed snapshot, not a live book. Positions are resolved to tickers via the filing’s identifiers and CUSIP mapping; unresolved lines are excluded. “Our call” is TENK/calls’s independent SEC-grounded verdict, not the fund’s view. No market-price data is used on this page.
Research and education only — not financial advice. TENKis not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities TENK rates; see Disclosures. Past performance does not guarantee future results. Do your own research.